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What is Flexeril?

Flexeril is the brand name of Cyclobenzaprine medication for muscle spasms from musculoskeletal conditions of sudden onset. It is available in a generic medicine and is helpful with rest and physical therapy to treat pain, injury, cramps, and other skeletal muscle conditions. It is not beneficial in cerebral palsy.

Flexeril is helpful to treat muscle spasms connected with physical therapy, which may occur because of acute musculoskeletal conditions. You should try not to take this medicine if you have thyroid, heart block, a heart rhythm disorder, congestive heart failure, or a recent heart attack—no recommendation for use more than a few weeks. It is for oral intake only. You can buy Flexeril online.

Muscle spasms occur to stabilize the body part affected during an injury; it prevents pain to prevent further damage. Flexeril treats such muscle spasms aligned to acute, painful musculoskeletal conditions. It is helpful along with other treatments for tetanus.

Important Information

You should avoid taking Flexeril if you have a heart block, thyroid disorder, heart rhythm disorder, congestive heart failure, or you recently had a heart attack. You can order Flexeril overnight.

Do not take Flexeril if you take an MAO inhibitor in the past two weeks, such as Tranylcypromine, Selegiline, Rasagiline, Phenelzine, Linezolid, or Isocarboxazid.

What to know before taking Flexeril?

Avoid drinking until you know how Flexeril will affect you. Dangerous side effects may occur if you continue drinking alcohol during the consumption of this medication. You can buy Flexeril online with a prescription.

If you are allergic to Flexeril, then you must not use it, or if you have:

  • A thyroid disorder
  • Heart rhythm disorder
  • Heart block
  • Congestive heart failure
  • A recent heart attack

It is not under recommendation for use by anyone younger than 15 years of age.

Don’t use Flexeril if you have taken an MAO inhibitor in the past two weeks because it may lead to a dangerous drug interaction. Isocarboxazid, phenelzine, linezolid, selegiline, rasagiline, and tranylcypromine come under MAO inhibitors.

If some medicine interacts with Flexeril, it may cause a severe condition known as serotonin syndrome. Ensure that your doctor knows if you also take stimulant medicine, herbal products, opioid medicine, or medicine for mental illness, depression, Parkinson’s disease, migraine headaches, serious infections, or to prevent nausea and vomiting. Prior Consult your doctor before making any changes regarding how and when you take medications.

Inform your doctor if you ever had liver disease, glaucoma, enlarged prostate, or urination problems to ensure that Flexeril is safe for you.

It is still unknown whether Flexeril will harm an unborn baby or not. Tell your doctor if you are expecting or planning to conceive. Do not breastfeed while taking this medicine.

Old age people are more sensitive to the effects of this medicine.

How to take Flexeril?

Take Flexeril precisely as per the doctor’s recommendation. Usually, doctors recommend taking it once daily for only two to three weeks. Follow all the directions in the prescription label and medication guides. Occasionally, your doctor may change your dosage.

Take medicine at the exact time each day. Call your medical healthcare provider if there is no improvement in your symptoms after three weeks of use or if they get worse. Store Flexeril away from heat and moisture at room temperature.

Flexeril dosage

Dosage information is only for Flexeril oral tablets. Your dosage, form, and strength of the drug and how often you take this medicine depend upon:

  • Your age,
  • your condition for which your treatment is going on
  • The seriousness of your condition
  • Your other medical conditions
  • How you react to the first dose

It is available in three strengths: 5 mg. 7.5 mg, 10 mg.

Dosage for relief of muscle spasms

  • Adult dosage (ages 18 to 64 years) – 5 to 10 mg three times per day.
  • Child dosage (ages 15 to 17 years) – 5 to 10 mg three times per day.
  • Child dosage (0-14 years) – not available

Senior dosage (ages 65 years and older) – due to the non-efficient working of the kidney at this age, the drugs’ processing may be slow in your body. And as a result, more of the drug stays in the body for a longer time. It raises your risk of side effects. The initial dosage for people under this age group is low or different from other dosing schedules. It can help to balance this drug in your body.

If you have moderate liver issues, your doctor may start you with a lower dose or a different dosing schedule. It can help in keeping levels of Flexeril from building up too much in your body. Never take this medication if you are suffering from moderate or severe liver problems.


In case of an overdose to Flexeril, take medical help or call the Poison helpline at 1-800-222-1222. An overdose of cyclobenzaprine can be deadly. Overdose symptoms of Flexeril may include vomiting, severe drowsiness, tremors, rapid heartbeats, agitation, or hallucinations.

What to avoid while using Flexeril?

Avoid consumption of alcohol because it can cause dangerous or deadly side effects.

Avoid driving any vehicle or performing any hazardous activity until you know this medicine’s effect on you. There could be an impairment in your reactions.

Flexeril side effects

Stop using Flexeril and urgently call your doctor if you have any of the following severe side effects:

  • Fast or irregular heartbeats;
  • Sudden weakness or numbness, balance problems, slurred speech; or
  • Chest pressure or pain spreading to your jaw or shoulder

Get medical attention immediately if you have any serotonin syndrome symptoms, such as:

  • Agitation,
  • Fever,
  • Hallucinations,
  • Shivering,
  • Sweating,
  • Muscle stiffness,
  • Rapid heart rate,
  • Loss of coordination,
  • Twitching,
  • Vomiting,
  • Nausea, or
  • Diarrhea

Common side effects of Flexeril may include dry mouth, tiredness, drowsiness, headache, dizziness, nausea, upset stomach, or constipation. Consult your doctor for medical advice regarding side effects—report side effects to the FDA at 1-800-FDA-1088.

Robaxin Vs. Flexeril

Both Robaxin and Flexeril belong to the skeletal muscle relaxants category of drugs. However, these muscle relaxants are not the same as they differ in composition and several other factors. Robaxin contains methocarbamol, while Flexeril contains cyclobenzaprine and comes in an extended-release form. Specific warnings for these medicines are the same such as they are not under prescription for pregnant women and may impair cognitive performance if abused.
When it comes to dosage, medical healthcare professionals usually prescribe Robaxin multiple times per day, while you can take Flexeril extended-release only one time a day. These drugs are comparable depending upon their effectiveness. But cyclobenzaprine (Flexeril) and tizanidine can be more sedating than Robaxin.

Flexeril and Alcohol

Flexeril relieves muscles spasms or pain and can be prescribed only to ease symptoms associated with neck pain, back pain, and tension headaches. If you are taking any muscle relaxants, you should avoid alcohol consumption.
Flexeril and alcohol both are likely to depress your central nervous system. They work to slow down brain activity, further slowing your heart rate and making your breathing shallow. And, no doubt they can make you feel sleepy or calm.

Tizanidine Vs. Flexeril

Tizanidine (or Zanaflex) is a new drug for relaxing muscles, and it helps treat muscle spasticity due to spinal cord injury & multiple sclerosis. The functioning of Tizanidine is to block the signals between motor nerves to relax muscle tone. The usual prescribed dose of this muscle relaxant is 2 mg or 4 mg tablet every six to eight hours.
On the other hand, Flexeril (or cyclobenzaprine) is also a muscle relaxant widely prescribed for acute, painful musculoskeletal problems such as neck or back pain. This effective drug works in the central nervous system to relieve muscle pain and spasms. Flexeril is available in immediate-release (IR) and extended-release (XR) forms.

What drugs can interact with Flexeril?

Using Flexeril with other drugs that cause drowsiness can worsen this effect. Ask your medical healthcare provider before taking opioid medication, a muscle relaxer, a sleeping pill, or any treatment for anxiety or seizures.

Various drugs may interact with Flexeril, including prescription and over-the-counter (OTC) medicines, herbal products, and vitamins.

FAQ’S (Frequently asked questions)

(Q.1) What is Flexeril used for?

Flexeril is used as a short-term medication for the treatment of muscle spasms. Medical healthcare providers worldwide prescribe this drug along with rest and physical therapy. It functions by relaxing the muscles which other relaxants fail to treat.

(Q.2) Is Flexeril a controlled substance?

No, the Drug Enforcement Administration (DEA) does not consider Flexeril a controlled substance. However, the medication does have a slight possibility for abuse by some because of its sedating effects.

(Q.3) Is Flexeril addictive?

Flexeril can be addictive if used for chronic pain support as it does not aid in inhibiting pain, but people may develop tolerance over time. It is addictive when some individuals try to get high with the help of this medication.

(Q.4) Can you take ibuprofen with flexeril?

You can take ibuprofen with Flexeril as no interactions were found between both of these drugs, but that does not mean no drug interaction exists. Always consult your medical healthcare provider before taking two medicines together.

(Q.5) Does Flexeril make you sleepy?

Flexeril is likely to cause sleepiness or impair your thinking and judgments. It may be beneficial for you to rest during the muscle spasm treatment; however, you should avoid driving, operating machinery, or performing tasks that need you to be mentally alert.

(Q.6) In general how long does Flexeril stay in your system?

According to the available estimates, after taking a Flexeril dose, it is most likely to leave out of your body within 5.5 days to 16.5 days depending upon various factors.
Flexeril has prolonged sustainability of between 1 to 3 days; it is basically the time your body takes to reduce the plasma drug level by almost half.
The elimination of Flexeril in the body is quite gradual. Typically, it takes around 5.5 X half-life for a drug elimination from your system.
So, according to the statements mentioned above, it is (5.5 by 1) 5.5 days to (5.5 by 3) 16.5 days for Flexeril sustenance in your system.